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Novel Drug Benefits Bone and Cartilage in Knee Osteoarthritis

An investigational selective cathepsin K inhibitor called MIV-711 failed to decrease knee osteoarthritis pain but attenuated bone area progression and reduced cartilage volume loss, a multicenter European trial reported in the Annals of Internal Medicine.

Drug and Nondrug Approaches for Treating Osteoarthritis

The American College of Rheumatology, in conjunction with the Arthritis Foundation, have issued updated treatment guidelines for osteoarthritis of the hand, hip and knee. In this slideshow, we highlight their recommendations for the use—or not—of drug and nondrug treatments that have been tested in clinical trials. These include strong recommendations for standard treatment options, such as weight loss and Tai Chi, and strong recommendations against treatments with pharmacologicals, such as glucosamine and chondroitin sulfate (except for hand osteoarthritis).

Carpal Tunnel Syndrome Causes, Symptoms, and Treatment

The carpal tunnel is a narrow passageway on the palm side of your wrist made up of bones and ligaments. The median nerve, which controls sensation and movement in the thumb and first three fingers, runs through this passageway along with tendons to the fingers and thumb. When it's pinched or compressed, the result is numbness, tingling, weakness, or pain in the hand, called carpal tunnel syndrome.

Imaging Can Mislead in Inflammatory Arthritis

MADRID — Too often, imaging tests lead to the overdiagnosis and excess treatment of inflammatory arthritis, leaving patients vulnerable to adverse drug effects with no improvement in outcome, according to a presentation here at the European League Against Rheumatism 2019 Congress.

Can the Mediterranean Diet Ward off Rheumatoid Arthritis?

High adherence to a Mediterranean diet reduced the odds of developing rheumatoid arthritis (RA) among men and among persons with seropositive RA, observed Swedish investigators in a recent large, population-based, case-control study.

Vibrating Gloves Significantly Reduce Osteoarthritis-Related Hand Pain

Gloves with small vibrating motors may safely reduce hand pain among women with osteoarthritis (OA) during and after use

Higher Body Fat, Obesity in Women Linked with RA

In women, higher body fat percentage, higher waist circumference (WC), and obesity were associated with higher risk of rheumatoid arthritis (RA), a recent study found. Researchers evaluated a population‐based prospective cohort study among 55,037 persons.

Early Exposure to Passive Smoke May Up Risk for RA Later in Life

Exposure to second-hand smoke during childhood was associated with an increased risk for developing rheumatoid arthritis (RA) later in life, researchers said.

Osteoarthritis: Can Vitamin and Mineral Supplements Help?

Patients with osteoarthritis often ask about the benefits of supplements. What will you tell them?

Here’s a look at the evidence behind vitamins D, K, and B; antioxidants; trace minerals; and glucosamine and chondroitin.